Biomedical Engineering · Vanderbilt University · Class of 2027

Chinonso Onuora

Medical device design and biomedical research, from adaptive pediatric mobility to physiological sensing.

chinonso.o.onuora@vanderbilt.eduLinkedIn

Projects

Research

Ethanol reinforcement in the Siciliano Lab at Vanderbilt. 3D-printed drug-delivery scaffolds in the Oyewumi Lab at NEOMED.

Clinical exposure

Hospice volunteer at Heart of Mary House since 2023, providing companionship and basic clinical care.

Education

B.E. in Biomedical Engineering, Vanderbilt University, expected May 2027. Premedical track.

← All projects

Project 01 · BME 2900WComplete

One-switch access to an interactive plush toy

A commercial interactive plush elephant, adapted so that one large external push switch triggers its peekaboo routine in place of small switches hidden in the legs. The adapted toy met all 8 design and ASTM F963-17 toy safety criteria and cost $77.53 to build, comparable to a $76.49 commercially adapted toy.

Course
BME 2900W
Standard
ASTM F963-17
Build cost
$77.53
Verification
8 of 8 criteria met
Plush elephant beside a large red push switch mounted on a clear plastic enclosure
Fig. 1.1 Adapted toy with its external switch.
  1. External push switch
  2. Switch enclosure
Gray plush elephant with pink ears seated on a lab bench
Fig. 1.2 Toy before modification.

Skills applied

  • Rewired the toy's activation circuit to an external push switch.
  • Soldered every new joint and insulated it with heat-shrink tubing.
  • Added a plug-and-jack breakaway connection to prevent cord entanglement.
  • Verified the build against design requirements and ASTM F963-17.
  • Benchmarked build cost against a commercially adapted toy.

Motivation

Standard push-button toys assume fine motor control that many children with motor, cognitive, or sensory impairments do not have. The objective was to improve access to play for children with limited dexterity while keeping the toy safe and affordable.

Technical details

  • Baseline toy: one push switch in each lower leg; either triggers audio and mechanical ear movement in a peekaboo or dancing routine.
  • The lead from the first internal switch was disconnected and soldered to the external switch, which sits in a small plastic enclosure.
  • The peekaboo routine is retained. Both internal switches and the dancing routine were removed.
  • Recommended next iteration: remove only one internal switch to preserve more play features, and reduce build labor.

Instructor: Dr. Eric C. Spivey.

Circuit schematic showing a battery source, two switches, two loads, and 1 kilohm resistors
Fig. 1.3 Toy switch circuit schematic.

For a closer look

Verification results8 Pass
Ref.RequirementAcceptance criterionEvidenceResult
Design requirements
DR-1Minimal effort to activateNumber of adult fingers needed to activate the toyActivated with fewer than two fingersPass
DR-2Minimal response timeSeconds from switch press to toy functionResponse-time criterion metPass
DR-3ReliabilityConsecutive activation cycles without failureReliability criterion metPass
ASTM F963-17 toy safety
§4.14.1Cords, straps, and elasticsAny cord shorter than 12 inMet through the §4.14.1.1 breakaway alternativePass
§4.14.1.1Breakaway featureNo cord without a breakaway featurePlug-and-jack connection separates under loadPass
§4.25.4Battery accessNo battery accessible without a screwdriverManufacturer battery compartment retainedPass
§4.25Strain reliefNo unsoldered electrical connectionsAll new connections solderedPass
§4.25Non-rechargeable cellsNo external power sourceNo external power source addedPass
Itemized cost (USD)$77.53
Plush toy26.99
Plastic switch enclosure2.00
Push switch8.60
Plug-and-jack wire3.50
Heat-shrink tubing0.03
String0.16
Labor36.25
Total$77.53

Comparable to a commercially adapted peekaboo toy from Adaptive Tech Solutions ($76.49). Labor accounted for nearly half of the build cost.

← All projects

Project 02 · BME 3900WComplete

A ride-on car converted into a powered mobility device

Our team of five converted a commercial 12 V ride-on car for a child with limited motor development: pressing a bar on the steering wheel drives the car, releasing it stops the car, and adjustable supports help the child stay upright. The build passed 7 of 8 verification criteria, with sideways stability still to be tested, and cost $444.97 against $3,999 for a pediatric power wheelchair. I developed the circuit schematics and shared in the soldering, drilling, and assembly.

Team
5 members
Report submitted
November 2025
Build cost
$444.97
Verification
7 passed · 1 not tested
Yellow ride-on car with a raised yellow foam seatback support and steering bar
Fig. 2.1 Adapted car.
  1. Adjustable postural support
Ride-on car cockpit with a green PVC bar fastened across the steering wheel
Fig. 2.2 Drive control at the steering wheel.
  1. PVC steering bar
  2. GO button at the wheel center, pressed by the bar

My contribution

  • Developed the circuit schematics of the stock and modified drive systems (Figs. 2.3 and 2.4).
  • Shared in soldering the new connections, drilling, and assembling the PVC steering bar and seat cushions.
  • Authored an individual design report on the team build.

Motivation

Powered wheelchairs are expensive, are seldom available to very young children, and are designed for transportation more than play. Following the Go Baby Go model from the University of Delaware, the objective was an affordable, safe, and customizable powered mobility device built from a commercial ride-on car. Stakeholders were children with developmental disabilities, parents and caregivers, physical therapists, and educators.

Technical details

  • Stock circuit: a fused 12 V battery powers a control board whose two relays set motor polarity for forward and reverse. The pedal acts as a push switch.
  • The pedal leads were cut, routed up the steering column, and soldered to the GO button. Horn and music buttons were removed; music remains on the dashboard.
  • The steering bar is fastened through the wheel with a metal connector and reinforced with polystyrene. Cut PVC ends are capped and taped.
  • Foam, yoga-block, and PVC supports attach to the seatback with Velcro, so they reposition as the child grows.
  • Recommended next iteration: test stability on a 10° incline with supports installed, and replace hot-glued attachments with mechanical fasteners.

Design team: Aidan Culp, William Ho, Baylie Theiler, Megan Woodworth, and Chinonso Onuora. Instructor: Dr. Eric C. Spivey.

Block diagram of battery, fuse, charger, control board, motors, gas pedal, and power button
Fig. 2.3 My schematic Stock drive circuit, with pedal input to the control board.
Block diagram with the gas pedal replaced by a button fitted to the steering wheel
Fig. 2.4 My schematic Modified drive circuit.
  1. Pedal input rerouted to a button on the steering wheel

For a closer look

Verification results7 Pass 1 Not tested
Ref.RequirementAcceptance criterionEvidenceResult
Design requirements
DR-1Reliable start and stopMoves when the steer bar is pressed; stops when pressure is releasedMovement began under pressure and stopped on releasePass
DR-2No inadvertent activationNo motion from a light tap or from steering aloneNo motion from light taps or across the full steering rangePass
DR-3Adjustable postural supportSupports are not rigidly fixedSupports reposition to accommodate growthPass
ASTM F963-17 toy safety
§4.7Accessible edgesNo potentially hazardous sharp edgesCut PVC ends capped and tapedPass
§4.14.1Cords, straps, and elasticsAny cord shorter than 12 inMet through the §4.14.1.1 alternativePass
§4.25.4Battery accessNo battery accessible without a screwdriverManufacturer battery compartment retainedPass
§4.25Strain reliefNo unsoldered electrical connectionsAll new connections solderedPass
§4.15.2.2Sideways stabilityNo tipping across a 10° inclineIncline fixture unavailable in the lab; recommended before clinical useNot tested
Itemized cost (USD)$444.97
BMW M4 12 V ride-on car299.00
PVC pipe and fittings17.40
Push switch8.60
Foam kickboard19.99
Hot glue gun and sticks9.99
Yoga blocks9.99
Yoga mat, ½ in13.74
Duct tape7.16
Five-point harness7.85
Polystyrene blocks6.25
Labor45.00
Total$444.97

Replication estimated at $400–$500 with market variation, compared with $3,999 for a pediatric power wheelchair (WHILL Model C2).

← All projects

Project 03 · BME 4901WComplete

A strap-on remote that makes ride-on cars accessible without modifying the car

Our team of five rebuilt a ride-on car's own remote control as a three-button input device that straps to the steering wheel, so a child with limited fine motor control can drive forward and steer with no change to the vehicle. It passed 12 of 13 verification criteria, with one partial pass for first-time pairing, at $80 in materials. I advocated for the soldered design the team adopted and helped rewire the battery pack.

Team
5 engineers
Report submitted
April 2026
Materials
$80 · target under $100–150
Verification
12 passed · 1 partial
Three-button remote strapped across the steering wheel of a black ride-on car
Fig. 3.1 Remote strapped to a ride-on car.
  1. Forward
  2. Left
  3. Right
  4. Velcro strap to the steering wheel
White housing with red, blue, and yellow large round buttons in a column
Fig. 3.2 Button panel with 60 mm caps.

My contribution

  • During concept selection, advocated with a teammate for bypassing the remote's buttons with soldered leads, over mechanical dowels that press them. The team adopted the soldered design after the dowel concept failed.
  • Helped rewire the remote's PCB to a compact two-AAA battery pack.
  • Helped sand the 3D-printed housing.
  • Co-authored the design report and co-presented the design review.

Motivation

Go Baby Go chapters and course builds such as Project 02 produce capable mobility devices, but they depend on a nearby chapter, volunteer skill, tools, and permanent changes to the car. Commercial pediatric power mobility costs over $2,000. The objective was a device a caregiver can install without tools or engineering skill.

Technical details

  • The remote's PCB was removed from its stock housing and repowered from a compact two-AAA pack.
  • Forward, left, and right are kept. Releasing forward stops the car, so a brake input is unnecessary; speed and reverse were removed.
  • Each large button closes the same circuit as the original PCB button, so the PCB transmits its original control signals unchanged.
  • The housing encloses the PCB, battery pack, and wiring and closes with sunk screws. Velcro straps through its slots let it move between cars.
  • Limitation: pairing with a car requires opening the housing once to press two internal buttons.
  • Next steps: user testing with children and caregivers, attachment testing on more steering wheels, adjustable button spacing, and extended cycle testing.

Design team: Charles Frech, Aidan Culp, Bridget Stevenson, Chinonso Onuora, and Hailey Frank. Instructor: Dr. Amanda Lowery.

White handheld ride-on car remote with small black buttons
Fig. 3.3 Stock remote with six small buttons.
Green circuit board inside an opened white remote housing
Fig. 3.4 PCB in the original housing; marked leads were cut to free the board.
Open 3D-printed white housing with three button bodies wired to a circuit board
Fig. 3.5 Internal wiring from the PCB to the three large buttons.
Schematic of three original PCB buttons each paired with a large external button
Fig. 3.6 Approach I advocated The soldered bypass: each large button is wired in parallel with an original PCB button.

For a closer look

Verification results12 Pass 1 Partial
Ref.RequirementAcceptance criterionEvidenceResult
Design requirements
DR-1Minimal physical effortButton activation force below 3.5 ozActivation force below 3.5 ozPass
DR-2Safe to useNo sharp edges; battery requires a tool to accessEdges sanded; battery enclosed behind screwsPass
DR-3Durable constructionWithstands 100+ activations without degradationFunction unchanged after drop testing; soldered connections. Extended cycle testing recommendedPass
DR-4Low costEstimated materials cost below $100–150$80 in materialsPass
DR-5Usable in group and classroom settingsNo exclusive setup requiredPairing with the car requires opening the housing once to press two internal buttonsPartial
DR-6Easy to cleanSmooth, waterproof, non-fabric exteriorSmooth PLA housing with flat surfacesPass
ASTM F963-17 toy safety
§4.7Accessible edgesNo accessible sharp edgesAll edges sanded, 3D-printed parts includedPass
§4.8ProjectionsNo exposed rigid pointsAll screws sunk flushPass
§4.14.1Cords, straps, and elasticsAny cord shorter than 12 inAll wiring internal and under 12 inPass
§4.25.4Battery accessNo battery accessible without a screwdriverBattery pack enclosed; screwdriver requiredPass
§4.25.10.8Strain reliefNo wire without strain reliefNo external wiringPass
§4.25Electrical connectionsAll connections soldered and heat-shrunkAll connections soldered and heat-shrunkPass
§4.15.2.2Sideways stabilityNo tipping across a 10° inclineController does not alter the car's center of gravityPass
Economic analysis (USD)$80 materials
18 AWG stranded wire12.00
Actuating buttons (×3)30.00
Velcro straps5.00
20 AWG stranded wire10.00
PLA filament13.00
Solder5.00
Hot glue sticks5.00
Tools (design lab access)0.00
Design labor (5 engineers × 12 h × $20/h)1,200.00
Total$1,280.00

Projected unit cost at commercial scale is $80, since design labor is not repeated per unit. Benchmark: Permobil Explorer Mini pediatric power mobility device, $2,944.

← All projects

Project 04 · BME 3302In development

A wearable muscle-fatigue sensor pairing EMG with salivary lactate

A wearable sensor for fitness applications, in development with one teammate, that tracks muscle fatigue by pairing surface electromyography with lactate measured noninvasively in saliva. The EMG channel is built and has recorded a first light-load trial with 20 detected repetitions; further results will be added as testing continues.

Team
2 · with Chloe Zhao
Status
Prototype · first EMG recording
Signals
Surface EMG · salivary lactate
Controller
ESP32 (Arduino)
An ESP32 development board on a perfboard wired to a small amplifier board with an 8-pin IC, resistors, a 3.5 mm jack, and two 9 V battery clips
Fig. 4.1 EMG acquisition prototype.
  1. ESP32 microcontroller
  2. EMG amplifier IC
  3. 3.5 mm jack
  4. 9 V battery clips

Skills in practice

  • Building an EMG amplifier on a solderable breadboard, read by an ESP32 microcontroller.
  • Filtering EMG to 20–500 Hz and detecting repetitions from a moving-RMS envelope.
  • Comparing loads by RMS amplitude and FFT-derived spectral frequency.
  • Pairing an electrophysiological signal with a biochemical marker of exertion.

Motivation

Muscle fatigue has both an electrical and a metabolic signature. Measuring surface EMG together with lactate links the electrical activity of the working muscle with its metabolic state.

Test protocol

  • Exercises performed to failure under light, medium, and heavy loads.
  • EMG compared across loads by RMS amplitude and spectral frequency to distinguish motor unit recruitment patterns.
  • In the first light-load recording, a repetition is counted where the moving-RMS envelope rises above the resting threshold (Fig. 4.3).

Instructor: Dr. Franz J. Baudenbacher.

Fig. 4.2 Signal chain for the two measurements.
Three stacked time-series plots of a 28 second EMG recording: raw signal, filtered signal with shaded analysis windows, and RMS envelope with 20 detected repetition peaks
Fig. 4.3 First light-load recording, with 20 repetitions detected. Top: raw signal at the ESP32 ADC. Middle: signal band-pass filtered to 20–500 Hz, with analysis windows shaded. Bottom: moving-RMS envelope with the resting threshold and detected repetitions. Scroll sideways to follow the recording.

About

Engineer in training, future physician-scientist

I am a premedical biomedical engineering student at Vanderbilt University and an undergraduate researcher. My design work centers on medical devices, and my laboratory work spans addiction pharmacology and drug-delivery biomaterials.

Laboratory research

Jan 2026 – present
Nashville, TN

Siciliano Lab, Vanderbilt University

Undergraduate Researcher

Investigating the central nervous system targets of ethanol by studying addiction-related behavior in mice, using oral self-administration and intravenous self-administration paradigms in behavioral chambers.

Evaluating how alcohol-metabolism inhibitors (4-methylpyrazole, sodium azide) alter drinking behavior to clarify the metabolic pathways underlying ethanol reinforcement.

Jun – Aug 2024
Rootstown, OH

Oyewumi Lab, Northeast Ohio Medical University

Research Fellow

Studied 3D-printed poly(lactic acid) scaffolds as a targeted drug-delivery platform, with a focus on protein loading and release kinetics. Evaluated loading and release of a model protein and a novel drug candidate by direct immersion and hydrogel-based methods.

Most Innovative Presentation · NEOMED Research Day 2024

Onuora C, Hessel E, Ghanta P, Oyewumi MO. Fabrication and characterization of 3D-printed scaffolds as a potential delivery platform to treat bone disorders. NEOMED Research Day, oral presentation, November 22, 2024.

Clinical exposure, teaching, and service

Sep 2023 – present
Nashville, TN

Heart of Mary House

Volunteer, non-profit hospice

Provide companionship and basic clinical care to residents with terminal illnesses, including medication administration and bathing.

Sep 2026 – present
Nashville, TN

Vanderbilt Athletics

Athletic Tutor

Provide one-on-one and small-group tutoring in STEM courses to Division I student-athletes balancing training and travel schedules.

Aug 2024 – Dec 2025
Nashville, TN

University Catholic

Sacristan

Prepared Masses and liturgical events; trained and organized altar servers.

Methods and tools
Device design
Circuit schematics, circuit modification and soldering, switch adaptation, mechanical assembly, ASTM F963-17 verification, cost analysis
Electronics
Circuit design, biosignal acquisition and processing, soldering
Laboratory
Intravenous self-administration (IVSA), rodent behavioral testing, fluorescence imaging, gel electrophoresis, sterile technique, chromatography, extraction, distillation, crystallization, IR spectroscopy
Computational
SolidWorks, MATLAB, GraphPad Prism, Java, Microsoft Office
Languages
French (upper intermediate)
Activities
Vanderbilt Commodore Orchestra, Anchor of Sound Pep Band, intramural ultimate frisbee